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Evidence against Stable Protein S-Nitrosylation as a Widespread Mechanism of Post-translational Regulation

S-nitrosation, commonly referred to as S-nitrosylation, is widely regarded as a ubiquitous, stable post-translational modification that directly regulates many proteins. Such a widespread role would appear to be incompatible with the inherent lability of the S-nitroso bond, especially its propensity...

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Detalles Bibliográficos
Autores principales: Wolhuter, Kathryn, Whitwell, Harry J., Switzer, Christopher H., Burgoyne, Joseph R., Timms, John F., Eaton, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807093/
https://www.ncbi.nlm.nih.gov/pubmed/29358077
http://dx.doi.org/10.1016/j.molcel.2017.12.019