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Gene-Specific Genetic Complementation between Brca1 and Cobra1 During Mouse Mammary Gland Development

Germ-line mutations in breast cancer susceptibility gene, BRCA1, result in familial predisposition to breast and ovarian cancers. The BRCA1 protein has multiple functional domains that interact with a variety of proteins in multiple cellular processes. Understanding the biological consequences of BR...

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Detalles Bibliográficos
Autores principales: Chiang, Huai-Chin, Zhang, Xiaowen, Zhao, Xiayan, Zhang, Chi, Chen, Jerry, Garza, Paula, Smith, Sabrina, Ludwig, Thomas, Baer, Richard J., Li, Rong, Hu, Yanfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807304/
https://www.ncbi.nlm.nih.gov/pubmed/29426838
http://dx.doi.org/10.1038/s41598-018-21044-2