Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and typically fatal lung disease with a very low survival rate. Excess accumulation of fibroblasts, myofibroblasts and extracellular matrix creates hypoxic conditions within the lungs, causing asphyxiation. Hypoxia is, therefore, one of t...

Descripción completa

Detalles Bibliográficos
Autores principales: Senavirathna, Lakmini Kumari, Huang, Chaoqun, Yang, Xiaoyun, Munteanu, Maria Cristina, Sathiaseelan, Roshini, Xu, Dao, Henke, Craig A., Liu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807313/
https://www.ncbi.nlm.nih.gov/pubmed/29426911
http://dx.doi.org/10.1038/s41598-018-21073-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807313/
https://www.ncbi.nlm.nih.gov/pubmed/29426911
http://dx.doi.org/10.1038/s41598-018-21073-x

Ejemplares similares