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Isolation and characterization of a minimal building block of polyubiquitin fibrils

As a posttranslational modifier, polyubiquitin is involved in the regulation of diverse intracellular processes; however, it is also found in pathological protein aggregates associated with Alzheimer’s disease and other neurodegenerative disorders. We previously observed that various types of polyub...

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Detalles Bibliográficos
Autores principales: Morimoto, Daichi, Walinda, Erik, Shinke, Mayo, Sugase, Kenji, Shirakawa, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807323/
https://www.ncbi.nlm.nih.gov/pubmed/29426858
http://dx.doi.org/10.1038/s41598-018-21144-z