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Microfluidic channel optimization to improve hydrodynamic dissociation of cell aggregates and tissue

Maximizing the speed and efficiency at which single cells can be liberated from tissues would dramatically advance cell-based diagnostics and therapies. Conventional methods involve numerous manual processing steps and long enzymatic digestion times, yet are still inefficient. In previous work, we d...

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Detalles Bibliográficos
Autores principales: Qiu, Xiaolong, Huang, Jen-Huang, Westerhof, Trisha M., Lombardo, Jeremy A., Henrikson, Katrina M., Pennell, Marissa, Pourfard, Pedram P., Nelson, Edward L., Nath, Pulak, Haun, Jered B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807353/
https://www.ncbi.nlm.nih.gov/pubmed/29426941
http://dx.doi.org/10.1038/s41598-018-20931-y