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Estimating dose-specific cell division and apoptosis rates from chemo-sensitivity experiments
In-vitro chemo-sensitivity experiments are an essential step in the early stages of cancer therapy development, but existing data analysis methods suffer from problems with fitting, do not permit assessment of uncertainty, and can give misleading estimates of cell growth inhibition. We present an ap...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807362/ https://www.ncbi.nlm.nih.gov/pubmed/29426887 http://dx.doi.org/10.1038/s41598-018-21017-5 |