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ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner

ZFP36 family members include ZFP36, ZFP36L1, and ZFP36L2, which belong to CCCH-type zinc finger proteins with two tandem zinc finger (TZF) regions. Whether ZFP36L1 and ZFP36L2 have antiproliferative activities similar to that of ZFP36 is unclear. In this study, when ZFP36L1 or ZFP36L2 was overexpres...

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Detalles Bibliográficos
Autores principales: Suk, Fat-Moon, Chang, Chi-Ching, Lin, Ren-Jye, Lin, Shyr-Yi, Liu, Shih-Chen, Jau, Chia-Feng, Liang, Yu-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807420/
https://www.ncbi.nlm.nih.gov/pubmed/29426877
http://dx.doi.org/10.1038/s41598-018-21160-z