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Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases

Protein aggregation critically affects cell viability in neurodegenerative diseases, but whether this also occurs in ischemic brain injury remains elusive. Prior studies report the post-ischemic aggregation of ubiquitin, small ubiquitin-related modifier (SUMO) and ribosomes, however whether other pr...

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Detalles Bibliográficos
Autores principales: Kahl, Anja, Blanco, Ismary, Jackman, Katherine, Baskar, Juhi, Milaganur Mohan, Harihar, Rodney-Sandy, Reunet, Zhang, Sheng, Iadecola, Costantino, Hochrainer, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807442/
https://www.ncbi.nlm.nih.gov/pubmed/29426953
http://dx.doi.org/10.1038/s41598-018-21063-z