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Spatiotemporal regulation of liver development by the Wnt/β-catenin pathway

While the Wnt/β-catenin pathway plays a critical role in the maintenance of the zonation of ammonia metabolizing enzymes in the adult liver, the mechanisms responsible for inducing zonation in the embryo are not well understood. Herein we address the spatiotemporal role of the Wnt/β-catenin pathway...

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Detalles Bibliográficos
Autores principales: Burke, Zoë D., Reed, Karen R., Yeh, Sheng-Wen, Meniel, Valerie, Sansom, Owen J., Clarke, Alan R., Tosh, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807466/
https://www.ncbi.nlm.nih.gov/pubmed/29426940
http://dx.doi.org/10.1038/s41598-018-20888-y