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Conformational states during vinculin unlocking differentially regulate focal adhesion properties

Focal adhesions (FAs) are multi-protein complexes that connect the actin cytoskeleton to the extracellular matrix, via integrin receptors. The growth, stability and adhesive functionality of these structures are tightly regulated by mechanical stress, yet, despite the extensive characterization of t...

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Detalles Bibliográficos
Autores principales: Chorev, Dror S., Volberg, Tova, Livne, Ariel, Eisenstein, Miriam, Martins, Bruno, Kam, Zvi, Jockusch, Brigitte M., Medalia, Ohad, Sharon, Michal, Geiger, Benny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807537/
https://www.ncbi.nlm.nih.gov/pubmed/29426917
http://dx.doi.org/10.1038/s41598-018-21006-8