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Genome-Wide Bimolecular Fluorescence Complementation-Based Proteomic Analysis of Toxoplasma gondii ROP18’s Human Interactome Shows Its Key Role in Regulation of Cell Immunity and Apoptosis

Toxoplasma gondii rhoptry protein ROP18 (TgROP18) is a key virulence factor secreted into the host cell during invasion, where it modulates the host cell response by interacting with its host targets. However, only a few TgROP18 targets have been identified. In this study, we applied a high-throughp...

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Detalles Bibliográficos
Autores principales: Xia, Jing, Kong, Ling, Zhou, Li-Juan, Wu, Shui-Zhen, Yao, Li-Jie, He, Cheng, He, Cynthia Y., Peng, Hong-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807661/
https://www.ncbi.nlm.nih.gov/pubmed/29459857
http://dx.doi.org/10.3389/fimmu.2018.00061