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Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade

BACKGROUND: Autoinflammatory disorders are distinguished by seemingly random episodes of systemic hyperinflammation, driven in particular by IL-1. Recent pre-clinical work has shown a key role for IL-1 in epilepsy in animal models, and therapies for autoinflammation including IL-1 blockade are propo...

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Detalles Bibliográficos
Autores principales: DeSena, Allen D., Do, Thuy, Schulert, Grant S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807745/
https://www.ncbi.nlm.nih.gov/pubmed/29426321
http://dx.doi.org/10.1186/s12974-018-1063-2