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Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade
BACKGROUND: Autoinflammatory disorders are distinguished by seemingly random episodes of systemic hyperinflammation, driven in particular by IL-1. Recent pre-clinical work has shown a key role for IL-1 in epilepsy in animal models, and therapies for autoinflammation including IL-1 blockade are propo...
Autores principales: | DeSena, Allen D., Do, Thuy, Schulert, Grant S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807745/ https://www.ncbi.nlm.nih.gov/pubmed/29426321 http://dx.doi.org/10.1186/s12974-018-1063-2 |
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