14, 15-EET induces breast cancer cell EMT and cisplatin resistance by up-regulating integrin αvβ3 and activating FAK/PI3K/AKT signaling

BACKGROUND: 14,15-epoxyeicosatrienoic acid (14,15-EET) is an important lipid signaling molecule involved in the regulation of tumor metastasis, however, the role and molecular mechanisms of 14,15-EET activity in breast cancer cell epithelial-mesenchymal transition (EMT) and drug resistance remain en...

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Detalles Bibliográficos
Autores principales: Luo, Jing, Yao, Jian-Feng, Deng, Xiao-Fei, Zheng, Xiao-Dan, Jia, Min, Wang, Yue-Qin, Huang, Yan, Zhu, Jian-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807756/
https://www.ncbi.nlm.nih.gov/pubmed/29426357
http://dx.doi.org/10.1186/s13046-018-0694-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807756/
https://www.ncbi.nlm.nih.gov/pubmed/29426357
http://dx.doi.org/10.1186/s13046-018-0694-6

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