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Precise genome-wide mapping of single nucleosomes and linkers in vivo

We developed a chemical cleavage method that releases single nucleosome dyad-containing fragments, allowing us to precisely map both single nucleosomes and linkers with high accuracy genome-wide in yeast. Our single nucleosome positioning data reveal that nucleosomes occupy preferred positions that...

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Detalles Bibliográficos
Autores principales: Chereji, Răzvan V., Ramachandran, Srinivas, Bryson, Terri D., Henikoff, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807854/
https://www.ncbi.nlm.nih.gov/pubmed/29426353
http://dx.doi.org/10.1186/s13059-018-1398-0