Silencing of HMGA2 reverses retardance of cell differentiation in human myeloid leukaemia

BACKGROUND: High-mobility group AT-hook 2 (HMGA2) may serve as an architectural transcription factor, and it can regulate a range of normal biological processes including proliferation and differentiation. Upregulation of HMGA2 expression is correlated to the undifferentiated phenotype of immature l...

Descripción completa

Detalles Bibliográficos
Autores principales: Tan, Li, Xu, Hongfa, Chen, Guoshu, Wei, Xiaoping, Yu, Baodan, Ye, Jingmei, Xu, Lihua, Tan, Huo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808023/
https://www.ncbi.nlm.nih.gov/pubmed/29384529
http://dx.doi.org/10.1038/bjc.2017.403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808023/
https://www.ncbi.nlm.nih.gov/pubmed/29384529
http://dx.doi.org/10.1038/bjc.2017.403

Ejemplares similares