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Silencing of HMGA2 reverses retardance of cell differentiation in human myeloid leukaemia

BACKGROUND: High-mobility group AT-hook 2 (HMGA2) may serve as an architectural transcription factor, and it can regulate a range of normal biological processes including proliferation and differentiation. Upregulation of HMGA2 expression is correlated to the undifferentiated phenotype of immature l...

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Detalles Bibliográficos
Autores principales:	Tan, Li, Xu, Hongfa, Chen, Guoshu, Wei, Xiaoping, Yu, Baodan, Ye, Jingmei, Xu, Lihua, Tan, Huo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808023/ https://www.ncbi.nlm.nih.gov/pubmed/29384529 http://dx.doi.org/10.1038/bjc.2017.403

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