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Treponema denticola chymotrypsin-like proteinase may contribute to orodigestive carcinogenesis through immunomodulation

BACKGROUND: Periodontal pathogens have been linked to oral and gastrointestinal (orodigestive) carcinogenesis. However, the exact mechanisms remain unknown. Treponema denticola (Td) is associated with severe periodontitis, a chronic inflammatory disease leading to tooth loss. The anaerobic spirochet...

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Detalles Bibliográficos
Autores principales: Nieminen, Mikko T, Listyarifah, Dyah, Hagström, Jaana, Haglund, Caj, Grenier, Daniel, Nordström, Dan, Uitto, Veli-Jukka, Hernandez, Marcela, Yucel-Lindberg, Tülay, Tervahartiala, Taina, Ainola, Mari, Sorsa, Timo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808028/
https://www.ncbi.nlm.nih.gov/pubmed/29149107
http://dx.doi.org/10.1038/bjc.2017.409