Alpha-synuclein alters differently gene expression of Sirts, PARPs and other stress response proteins: implications for neurodegenerative disorders

Alpha-synuclein (ASN) is a presynaptic protein that can easily change its conformation under different types of stress. It’s assumed that ASN plays an important role in the pathogenesis of Parkinson’s and Alzheimer’s disease. However, the molecular mechanism of ASN toxicity has not been elucidated....

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Detalles Bibliográficos
Autores principales: Motyl, J., Wencel, P. L., Cieślik, M., Strosznajder, R. P., Strosznajder, J. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808059/
https://www.ncbi.nlm.nih.gov/pubmed/28050792
http://dx.doi.org/10.1007/s12035-016-0317-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808059/
https://www.ncbi.nlm.nih.gov/pubmed/28050792
http://dx.doi.org/10.1007/s12035-016-0317-1

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