Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation

The enzyme imidazole glycerol phosphate synthase (IGPS) is a model for studies of long-range allosteric regulation in enzymes. Binding of the allosteric effector ligand N'-[5'-phosphoribulosyl)formimino]-5-aminoimidazole-4-carboxamide-ribonucleotide (PRFAR) stimulates millisecond (ms) time...

Descripción completa

Detalles Bibliográficos
Autores principales: Lisi, George P., Currier, Allen A., Loria, J. Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808140/
https://www.ncbi.nlm.nih.gov/pubmed/29468164
http://dx.doi.org/10.3389/fmolb.2018.00004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808140/
https://www.ncbi.nlm.nih.gov/pubmed/29468164
http://dx.doi.org/10.3389/fmolb.2018.00004

Ejemplares similares