Additive Dose Response Models: Explicit Formulation and the Loewe Additivity Consistency Condition

High-throughput techniques allow for massive screening of drug combinations. To find combinations that exhibit an interaction effect, one filters for promising compound combinations by comparing to a response without interaction. A common principle for no interaction is Loewe Additivity which is bas...

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Detalles Bibliográficos
Autores principales: Lederer, Simone, Dijkstra, Tjeerd M. H., Heskes, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808155/
https://www.ncbi.nlm.nih.gov/pubmed/29467650
http://dx.doi.org/10.3389/fphar.2018.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808155/
https://www.ncbi.nlm.nih.gov/pubmed/29467650
http://dx.doi.org/10.3389/fphar.2018.00031

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