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Additive Dose Response Models: Explicit Formulation and the Loewe Additivity Consistency Condition
High-throughput techniques allow for massive screening of drug combinations. To find combinations that exhibit an interaction effect, one filters for promising compound combinations by comparing to a response without interaction. A common principle for no interaction is Loewe Additivity which is bas...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808155/ https://www.ncbi.nlm.nih.gov/pubmed/29467650 http://dx.doi.org/10.3389/fphar.2018.00031 |