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Functional G-Protein-Coupled Receptor (GPCR) Synthesis: The Pharmacological Analysis of Human Histamine H1 Receptor (HRH1) Synthesized by a Wheat Germ Cell-Free Protein Synthesis System Combined with Asolectin Glycerosomes

G-protein-coupled receptors (GPCRs) are membrane proteins distributed on the cell surface, and they may be potential drug targets. However, synthesizing GPCRs in vitro can be challenging. Recently, some cell-free protein synthesis systems have been shown to produce a large amount of membrane protein...

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Detalles Bibliográficos
Autores principales: Suzuki, Yasuyuki, Ogasawara, Tomio, Tanaka, Yuki, Takeda, Hiroyuki, Sawasaki, Tatsuya, Mogi, Masaki, Liu, Shuang, Maeyama, Kazutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808195/
https://www.ncbi.nlm.nih.gov/pubmed/29467651
http://dx.doi.org/10.3389/fphar.2018.00038