TNF-α Increases Production of Reactive Oxygen Species through Cdk5 Activation in Nociceptive Neurons

The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. We reported earlier a key role of Cyclin-dependent kinase 5 (Cdk5) during i...

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Detalles Bibliográficos
Autores principales: Sandoval, Rodrigo, Lazcano, Pablo, Ferrari, Franco, Pinto-Pardo, Nicolás, González-Billault, Christian, Utreras, Elías
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808211/
https://www.ncbi.nlm.nih.gov/pubmed/29467671
http://dx.doi.org/10.3389/fphys.2018.00065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808211/
https://www.ncbi.nlm.nih.gov/pubmed/29467671
http://dx.doi.org/10.3389/fphys.2018.00065

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