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TNF-α Increases Production of Reactive Oxygen Species through Cdk5 Activation in Nociceptive Neurons
The participation of reactive oxygen species (ROS) generated by NOX1 and NOX2/NADPH oxidase has been documented during inflammatory pain. However, the molecular mechanism involved in their activation is not fully understood. We reported earlier a key role of Cyclin-dependent kinase 5 (Cdk5) during i...
Autores principales: | Sandoval, Rodrigo, Lazcano, Pablo, Ferrari, Franco, Pinto-Pardo, Nicolás, González-Billault, Christian, Utreras, Elías |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808211/ https://www.ncbi.nlm.nih.gov/pubmed/29467671 http://dx.doi.org/10.3389/fphys.2018.00065 |
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