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Tolerance and Tachyphylaxis to Head Twitches Induced by the 5-HT2A Agonist 25CN-NBOH in Mice

The serotonin (5-HT) 2A receptor is the primary molecular target of serotonergic hallucinogens, which trigger large-scale perturbations of the cortex. Our understanding of how 5-HT(2A) activation may cause the effects of hallucinogens has been hampered by the receptor unselectivity of most of the dr...

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Detalles Bibliográficos
Autores principales: Buchborn, Tobias, Lyons, Taylor, Knöpfel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808243/
https://www.ncbi.nlm.nih.gov/pubmed/29467649
http://dx.doi.org/10.3389/fphar.2018.00017