The Steroid Hormone 20-Hydroxyecdysone Regulates the Conjugation of Autophagy-Related Proteins 12 and 5 in a Concentration and Time-Dependent Manner to Promote Insect Midgut Programmed Cell Death

Autophagy requires the conjugation of autophagy-related protein 12 (ATG12) to autophagy-related protein 5 (ATG5) through covalent attachment. However, the signals regulating ATG12–ATG5 conjugation are unclear. The larval midgut of lepidopteran insects performs autophagy and apoptosis sequentially du...

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Detalles Bibliográficos
Autores principales: Li, Yong-Bo, Yang, Ting, Wang, Jin-Xing, Zhao, Xiao-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808327/
https://www.ncbi.nlm.nih.gov/pubmed/29467720
http://dx.doi.org/10.3389/fendo.2018.00028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808327/
https://www.ncbi.nlm.nih.gov/pubmed/29467720
http://dx.doi.org/10.3389/fendo.2018.00028

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