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Acid-Sensing Ion Channel 1a Regulates Fate of Rat Nucleus Pulposus Cells in Acid Stimulus Through Endoplasmic Reticulum Stress

Acid-sensing ion channel 1a (ASIC1a) participates in human intervertebral disc degeneration (IVDD) and regulates the destiny of nucleus pulposus cells (NPCs) in acid stimulus. However, the mechanism of ASIC1a activation and its downstream pathway remain unclear. Endoplasmic reticulum (ER) stress als...

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Detalles Bibliográficos
Autores principales: Xie, Zhi-Yang, Chen, Lu, Zhang, Cong, Liu, Lei, Wang, Feng, Cai, Feng, Wang, Xiao-Hu, Shi, Rui, Sinkemani, Arjun, Yu, Hao-Min, Hong, Xin, Wu, Xiao-Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808393/
https://www.ncbi.nlm.nih.gov/pubmed/29445584
http://dx.doi.org/10.1089/biores.2017.0049