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Acid-Sensing Ion Channel 1a Regulates Fate of Rat Nucleus Pulposus Cells in Acid Stimulus Through Endoplasmic Reticulum Stress
Acid-sensing ion channel 1a (ASIC1a) participates in human intervertebral disc degeneration (IVDD) and regulates the destiny of nucleus pulposus cells (NPCs) in acid stimulus. However, the mechanism of ASIC1a activation and its downstream pathway remain unclear. Endoplasmic reticulum (ER) stress als...
Autores principales: | Xie, Zhi-Yang, Chen, Lu, Zhang, Cong, Liu, Lei, Wang, Feng, Cai, Feng, Wang, Xiao-Hu, Shi, Rui, Sinkemani, Arjun, Yu, Hao-Min, Hong, Xin, Wu, Xiao-Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808393/ https://www.ncbi.nlm.nih.gov/pubmed/29445584 http://dx.doi.org/10.1089/biores.2017.0049 |
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