Coupling the recombineering to Cre-lox system enables simplified large-scale genome deletion in Lactobacillus casei

BACKGROUND: Lactobacillus casei is widely used in the dairy and pharmaceutical industries and a promising candidate for use as cell factories. Recently, genome sequencing and functional genomics provide the possibility for reducing L. casei genome. However, it was still limited by the inefficient an...

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Detalles Bibliográficos
Autores principales: Xin, Yongping, Guo, Tingting, Mu, Yingli, Kong, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808424/
https://www.ncbi.nlm.nih.gov/pubmed/29433512
http://dx.doi.org/10.1186/s12934-018-0872-4

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