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Randomized, Prospective Double-Blinded Study Comparing 3 Different Doses of 5-Aminolevulinic Acid for Fluorescence-Guided Resections of Malignant Gliomas

BACKGROUND: Five-aminolevulinic acid (5-ALA) is used for fluorescence-guided resections of malignant glioma at a dose of 20 mg/kg; yet, it is unknown whether lower doses may also provide efficacy. OBJECTIVE: To perform a double-blinded randomized study comparing 3 different doses of 5-ALA. METHODS:...

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Detalles Bibliográficos
Autores principales: Stummer, Walter, Stepp, Herbert, Wiestler, Otmar D., Pichlmeier, Uwe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808499/
https://www.ncbi.nlm.nih.gov/pubmed/28379547
http://dx.doi.org/10.1093/neuros/nyx074