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Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

Ciliary trafficking defects are the underlying cause of many ciliopathies, including Retinitis Pigmentosa (RP). Anterograde intraflagellar transport (IFT) is mediated by kinesin motor proteins; however, the function of the homodimeric Kif17 motor in cilia is poorly understood, whereas Kif7 is known...

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Detalles Bibliográficos
Autores principales: Schwarz, Nele, Lane, Amelia, Jovanovic, Katarina, Parfitt, David A., Aguila, Monica, Thompson, Clare L., da Cruz, Lyndon, Coffey, Peter J., Chapple, J. Paul, Hardcastle, Alison J., Cheetham, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808637/
https://www.ncbi.nlm.nih.gov/pubmed/28444310
http://dx.doi.org/10.1093/hmg/ddx143