Cargando…

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins

Mostrar otras versiones (1)

Ciliary trafficking defects are the underlying cause of many ciliopathies, including Retinitis Pigmentosa (RP). Anterograde intraflagellar transport (IFT) is mediated by kinesin motor proteins; however, the function of the homodimeric Kif17 motor in cilia is poorly understood, whereas Kif7 is known...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schwarz, Nele, Lane, Amelia, Jovanovic, Katarina, Parfitt, David A., Aguila, Monica, Thompson, Clare L., da Cruz, Lyndon, Coffey, Peter J., Chapple, J. Paul, Hardcastle, Alison J., Cheetham, Michael E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5808637/ https://www.ncbi.nlm.nih.gov/pubmed/28444310 http://dx.doi.org/10.1093/hmg/ddx143

Ejemplares similares

Arl3 and RP2 regulate the trafficking of ciliary tip kinesins
por: Schwarz, Nele, et al.
Publicado: (2017)

Translational read-through of the RP2 Arg120stop mutation in patient iPSC-derived retinal pigment epithelium cells
por: Schwarz, Nele, et al.
Publicado: (2015)

Modeling and Rescue of RP2 Retinitis Pigmentosa Using iPSC-Derived Retinal Organoids
por: Lane, Amelia, et al.
Publicado: (2020)

Separable roles for RanGTP in nuclear and ciliary trafficking of a kinesin-2 subunit
por: Huang, Shengping, et al.
Publicado: (2020)

Identification and Correction of Mechanisms Underlying Inherited Blindness in Human iPSC-Derived Optic Cups
por: Parfitt, David A., et al.
Publicado: (2016)

Ciliary ARL13B prevents obesity in mice
por: Terry, Tiffany T., et al.
Publicado: (2023)

Arl8 and SKIP Act Together to Link Lysosomes to Kinesin-1
por: Rosa-Ferreira, Cláudia, et al.
Publicado: (2011)

The X-linked Retinitis Pigmentosa protein RP2 facilitates traffic of cilia target proteins
por: Schwarz, N, et al.
Publicado: (2012)

ARL3 and ARL13B GTPases participate in distinct steps of INPP5E targeting to the ciliary membrane
por: Fujisawa, Sayaka, et al.
Publicado: (2021)

Ciliary ARL13B inhibits developmental kidney cystogenesis in mouse
por: Van Sciver, Robert E., et al.
Publicado: (2023)

ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition
por: Alkanderi, Sumaya, et al.
Publicado: (2018)

A G-protein activation cascade from Arl13B to Arl3 and implications for ciliary targeting of lipidated proteins
por: Gotthardt, Katja, et al.
Publicado: (2015)

Hedgehog-induced ciliary trafficking of kinesin-4 motor KIF7 requires intraflagellar transport but not KIF7’s microtubule binding
por: Yue, Yang, et al.
Publicado: (2022)

SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors
por: Li, Yujie, et al.
Publicado: (2013)

SUMOylation of the small GTPase ARL-13 promotes ciliary targeting of sensory receptors
por: Li, Yujie, et al.
Publicado: (2012)

The Interaction of CCDC104/BARTL1 with Arl3 and Implications for Ciliary Function
por: Lokaj, Mandy, et al.
Publicado: (2015)

Active Transport and Diffusion Barriers Restrict Joubert Syndrome-Associated ARL13B/ARL-13 to an Inv-like Ciliary Membrane Subdomain
por: Cevik, Sebiha, et al.
Publicado: (2013)

Arl13b regulates early endocytic vesicle trafficking
por: Barral, DC, et al.
Publicado: (2012)

Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration
por: Travis, Amanda M, et al.
Publicado: (2023)

Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry
por: Qiu, Hantian, et al.
Publicado: (2021)

RP2-Associated X-linked Retinopathy: Clinical Findings, Molecular Genetics, and Natural History
por: Georgiou, Michalis, et al.
Publicado: (2023)

The unusual flagellar-targeting mechanism and functions of the trypanosome ortholog of the ciliary GTPase Arl13b
por: Zhang, Yiliu, et al.
Publicado: (2018)

Novel homozygous splicing mutations in ARL2BP cause autosomal recessive retinitis pigmentosa
por: Fiorentino, Alessia, et al.
Publicado: (2018)

Hydrogen peroxide induces Arl1 degradation and impairs Golgi-mediated trafficking
por: Ireland, Stephen C., et al.
Publicado: (2020)

Are kinesins required for organelle trafficking in plant cells?
por: Cai, Giampiero, et al.
Publicado: (2012)

Functions of Kinesin Superfamily Proteins in Neuroreceptor Trafficking
por: Wang, Na, et al.
Publicado: (2015)

Dynamics of the IFT machinery at the ciliary tip
por: Chien, Alexander, et al.
Publicado: (2017)

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
por: Cevik, Sebiha, et al.
Publicado: (2010)

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans
por: Cevik, Sebiha, et al.
Publicado: (2010)

The Ciliary Protein Arl13b Functions Outside of the Primary Cilium in Shh-Mediated Axon Guidance
por: Ferent, Julien, et al.
Publicado: (2019)

ARL3 mediates BBSome ciliary turnover by promoting its outward movement across the transition zone
por: Liu, Yan-Xia, et al.
Publicado: (2022)

Increasing Ciliary ARL13B Expression Drives Active and Inhibitor-Resistant Smoothened and GLI into Glioma Primary Cilia
por: Shi, Ping, et al.
Publicado: (2023)

Regulators of kinesin involved in polarized trafficking and axon outgrowth
por: Luo, Shuo, et al.
Publicado: (2006)

Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation
por: Wu, Ping-Hsiu, et al.
Publicado: (2020)

The nphp-2 and arl-13 Genetic Modules Interact to Regulate Ciliogenesis and Ciliary Microtubule Patterning in C. elegans
por: Warburton-Pitt, Simon R. F., et al.
Publicado: (2014)

Axoneme polyglutamylation regulated by Joubert syndrome protein ARL13B controls ciliary targeting of signaling molecules
por: He, Kai, et al.
Publicado: (2018)

The Developmental Process of the Growing Motile Ciliary Tip Region
por: Reynolds, Matthew J., et al.
Publicado: (2018)

The ciliary lumen accommodates passive diffusion and vesicle-assisted trafficking in cytoplasm–ciliary transport
por: Ruba, Andrew, et al.
Publicado: (2023)

Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5
por: Shi, Meng, et al.
Publicado: (2018)

Functional exploration of heterotrimeric kinesin-II in IFT and ciliary length control in Chlamydomonas
por: Li, Shufen, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ddseu6gji0mein1irlln05ich5