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Genetic association of -1562C>T polymorphism in the MMP9 gene with primary glaucoma in a north Indian population

MMP (Matrix metalloproteinase) 9 is reported to affect glaucoma pathogenesis by altering intraocular pressure (IOP) through its role in remodeling the extracellular matrix (ECM) in the trabecular meshwork. A genetic variant at the promoter region in the MMP9 gene (-1562C>T) has a putative role in...

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Detalles Bibliográficos
Autores principales: Thakur, Nanamika, Kupani, Manu, Pandey, Rajeev Kumar, Mannan, Rashim, Pruthi, Archna, Mehrotra, Sanjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809065/
https://www.ncbi.nlm.nih.gov/pubmed/29432439
http://dx.doi.org/10.1371/journal.pone.0192636