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Probing the role of intercalating protein sidechains for kink formation in DNA

Protein binding can induce DNA kinks, which are for example important to enhance the specificity of the interaction and to facilitate the assembly of multi protein complexes. The respective proteins frequently exhibit amino acid sidechains that intercalate between the DNA base steps at the site of t...

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Detalles Bibliográficos
Autores principales: Sandmann, Achim, Sticht, Heinrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809078/
https://www.ncbi.nlm.nih.gov/pubmed/29432448
http://dx.doi.org/10.1371/journal.pone.0192605