Phenotypic diversity and temporal variability in a bacterial signaling network revealed by single-cell FRET

We present in vivo single-cell FRET measurements in the Escherichia coli chemotaxis system that reveal pervasive signaling variability, both across cells in isogenic populations and within individual cells over time. We quantify cell-to-cell variability of adaptation, ligand response, as well as ste...

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Detalles Bibliográficos
Autores principales: Keegstra, Johannes M, Kamino, Keita, Anquez, François, Lazova, Milena D, Emonet, Thierry, Shimizu, Thomas S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Computational and Systems Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809149/
https://www.ncbi.nlm.nih.gov/pubmed/29231170
http://dx.doi.org/10.7554/eLife.27455

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809149/
https://www.ncbi.nlm.nih.gov/pubmed/29231170
http://dx.doi.org/10.7554/eLife.27455

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