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Phenotypic diversity and temporal variability in a bacterial signaling network revealed by single-cell FRET
We present in vivo single-cell FRET measurements in the Escherichia coli chemotaxis system that reveal pervasive signaling variability, both across cells in isogenic populations and within individual cells over time. We quantify cell-to-cell variability of adaptation, ligand response, as well as ste...
Autores principales: | Keegstra, Johannes M, Kamino, Keita, Anquez, François, Lazova, Milena D, Emonet, Thierry, Shimizu, Thomas S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809149/ https://www.ncbi.nlm.nih.gov/pubmed/29231170 http://dx.doi.org/10.7554/eLife.27455 |
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