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Hydrogels with precisely controlled integrin activation dictate vascular patterning and permeability

Integrin binding to bioengineered hydrogel scaffolds is essential for tissue regrowth and regeneration, yet not all integrin binding can lead to tissue repair. Here, we show that through engineering hydrogel materials to promote α3/α5β1 integrin binding, we can promote the formation of a space filli...

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Detalles Bibliográficos
Autores principales: Li, Shuoran, Nih, Lina R., Bachman, Haylee, Fei, Peng, Li, Yilei, Nam, Eunwoo, Dimatteo, Robert, Carmichael, S. Thomas, Barker, Thomas H., Segura, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809173/
https://www.ncbi.nlm.nih.gov/pubmed/28783156
http://dx.doi.org/10.1038/nmat4954