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Impaired Control of Epstein–Barr Virus Infection in B-Cell Expansion with NF-κB and T-Cell Anergy Disease
B-cell expansion with NF-κB and T-cell anergy (BENTA) disease is a B-cell-specific lymphoproliferative disorder caused by germline gain-of-function mutations in CARD11. These mutations force the CARD11 scaffold into an open conformation capable of stimulating constitutive NF-κB activation in lymphoc...
主要な著者: | , , , |
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フォーマット: | Online 論文 テキスト |
言語: | English |
出版事項: |
Frontiers Media S.A.
2018
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主題: | |
オンライン・アクセス: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809398/ https://www.ncbi.nlm.nih.gov/pubmed/29472930 http://dx.doi.org/10.3389/fimmu.2018.00198 |