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The Antimicrobial Activity of a Carbon Monoxide Releasing Molecule (EBOR-CORM-1) Is Shaped by Intraspecific Variation within Pseudomonas aeruginosa Populations

Carbon monoxide releasing molecules (CORMs) have been suggested as a new synthetic class of antimicrobials to treat bacterial infections. Here we utilized a novel EBOR-CORM-1 ([NEt(4)][MnBr(2)(CO)(4)]) capable of water-triggered CO-release, and tested its efficacy against a collection of clinical Ps...

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Detalles Bibliográficos
Autores principales: Flanagan, Lindsey, Steen, Rachel R., Saxby, Karinna, Klatter, Mirre, Aucott, Benjamin J., Winstanley, Craig, Fairlamb, Ian J. S., Lynam, Jason M., Parkin, Alison, Friman, Ville-Petri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809400/
https://www.ncbi.nlm.nih.gov/pubmed/29472912
http://dx.doi.org/10.3389/fmicb.2018.00195