Non-equivalent antigen presenting capabilities of dendritic cells and macrophages in generating brain-infiltrating CD8(+) T cell responses

The contribution of antigen-presenting cell (APC) types in generating CD8(+) T cell responses in the central nervous system (CNS) is not fully defined, limiting the development of vaccines and understanding of immune-mediated neuropathology. Here, we generate a transgenic mouse that enables cell-spe...

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Detalles Bibliográficos
Autores principales: Malo, Courtney S., Huggins, Matthew A., Goddery, Emma N., Tolcher, Heather M. A., Renner, Danielle N., Jin, Fang, Hansen, Michael J., Pease, Larry R., Pavelko, Kevin D., Johnson, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809416/
https://www.ncbi.nlm.nih.gov/pubmed/29434238
http://dx.doi.org/10.1038/s41467-018-03037-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809416/
https://www.ncbi.nlm.nih.gov/pubmed/29434238
http://dx.doi.org/10.1038/s41467-018-03037-x

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