Dendritic Cell Migration to Skin-Draining Lymph Nodes Is Controlled by Dermatan Sulfate and Determines Adaptive Immunity Magnitude

For full activation of naïve adaptive lymphocytes in skin-draining lymph nodes (LNs), presentation of peptide:MHC complexes by LN-resident and skin-derived dendritic cells (DCs) that encountered antigens (Ags) is an absolute prerequisite. To get to the nearest draining LN upon intradermal immunizati...

Descripción completa

Detalles Bibliográficos
Autores principales: Nadafi, Reza, Koning, Jasper J., Veninga, Henrike, Stachtea, Xanthi N., Konijn, Tanja, Zwiers, Antonie, Malmström, Anders, den Haan, Joke M. M., Mebius, Reina E., Maccarana, Marco, Reijmers, Rogier M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809438/
https://www.ncbi.nlm.nih.gov/pubmed/29472931
http://dx.doi.org/10.3389/fimmu.2018.00206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809438/
https://www.ncbi.nlm.nih.gov/pubmed/29472931
http://dx.doi.org/10.3389/fimmu.2018.00206

Ejemplares similares