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Three-dimensional (3D) tetra-culture brain on chip platform for organophosphate toxicity screening

Organophosphate-based compounds (OPs) represent a significant threat to warfighters (nerve agents) and civilian populations (pesticides). There is a pressing need to develop in vitro brain models that correlate to the in vivo brain to rapidly study OPs for neurotoxicity. Here we report on a microflu...

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Detalles Bibliográficos
Autores principales: Koo, Youngmi, Hawkins, Brian T., Yun, Yeoheung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809488/
https://www.ncbi.nlm.nih.gov/pubmed/29434277
http://dx.doi.org/10.1038/s41598-018-20876-2