Murine hematopoietic stem cell reconstitution potential is maintained by osteopontin during aging

In adult mammals, hematopoietic stem cells (HSCs) reside in the bone marrow and are in part regulated by the bone marrow microenvironment, called the stem cell niche. We have previously identified the bone marrow morphogen osteopontin (OPN), which is abundantly present in the bone marrow extracellul...

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Detalles Bibliográficos
Autores principales: Li, Jin, Carrillo García, Carmen, Riedt, Tamara, Brandes, Maria, Szczepanski, Sabrina, Brossart, Peter, Wagner, Wolfgang, Janzen, Viktor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809550/
https://www.ncbi.nlm.nih.gov/pubmed/29434282
http://dx.doi.org/10.1038/s41598-018-21324-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809550/
https://www.ncbi.nlm.nih.gov/pubmed/29434282
http://dx.doi.org/10.1038/s41598-018-21324-x

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