Modeling Congenital Adrenal Hyperplasia and Testing Interventions for Adrenal Insufficiency Using Donor-Specific Reprogrammed Cells

Adrenal insufficiency is managed by hormone replacement therapy, which is far from optimal; the ability to generate functional steroidogenic cells would offer a unique opportunity for a curative approach to restoring the complex feedback regulation of the hypothalamic-pituitary-adrenal axis. Here, w...

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Detalles Bibliográficos
Autores principales: Ruiz-Babot, Gerard, Balyura, Mariya, Hadjidemetriou, Irene, Ajodha, Sharon J., Taylor, David R., Ghataore, Lea, Taylor, Norman F., Schubert, Undine, Ziegler, Christian G., Storr, Helen L., Druce, Maralyn R., Gevers, Evelien F., Drake, William M., Srirangalingam, Umasuthan, Conway, Gerard S., King, Peter J., Metherell, Louise A., Bornstein, Stefan R., Guasti, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809617/
https://www.ncbi.nlm.nih.gov/pubmed/29386111
http://dx.doi.org/10.1016/j.celrep.2018.01.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809617/
https://www.ncbi.nlm.nih.gov/pubmed/29386111
http://dx.doi.org/10.1016/j.celrep.2018.01.003

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