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Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir
Antiretroviral therapy cannot cure HIV-1 infection due to the persistence of a small number of latently infected cells harboring replication-competent proviruses. Measuring persistent HIV-1 is challenging, as it consists of a mosaic population of defective and intact proviruses that can shift from a...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810003/ https://www.ncbi.nlm.nih.gov/pubmed/29433524 http://dx.doi.org/10.1186/s12977-018-0404-7 |