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Measuring replication competent HIV-1: advances and challenges in defining the latent reservoir

Antiretroviral therapy cannot cure HIV-1 infection due to the persistence of a small number of latently infected cells harboring replication-competent proviruses. Measuring persistent HIV-1 is challenging, as it consists of a mosaic population of defective and intact proviruses that can shift from a...

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Detalles Bibliográficos
Autores principales:	Wang, Zheng, Simonetti, Francesco R., Siliciano, Robert F., Laird, Gregory M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810003/ https://www.ncbi.nlm.nih.gov/pubmed/29433524 http://dx.doi.org/10.1186/s12977-018-0404-7

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