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Metabotropic glutamate receptor 5 tracer [(18)F]-FPEB displays increased binding potential in postcentral gyrus and cerebellum of male individuals with autism: a pilot PET study

BACKGROUND: Autism is a neurodevelopmental disorder that is first manifested during early childhood. Postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mGluR5) in cerebellar vermis and prefrontal cortex of individuals with autism. METHODS:...

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Detalles Bibliográficos
Autores principales: Fatemi, S. Hossein, Wong, Dean F., Brašić, James R., Kuwabara, Hiroto, Mathur, Anil, Folsom, Timothy D., Jacob, Suma, Realmuto, George M., Pardo, José V., Lee, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810020/
https://www.ncbi.nlm.nih.gov/pubmed/29449954
http://dx.doi.org/10.1186/s40673-018-0082-1