CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells

CXCR4 was the first receptor identified for CXCL12, but a second receptor, CXCR7, has also been described and its function in hematopoietic cells remains unknown. By inhibition of CXCR4 and/or CXCR7, we showed that CXCR7 participates in normal CD34(+) and U937 cell migration and prevents downregulat...

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Detalles Bibliográficos
Autores principales: Melo, Rita de Cassia Carvalho, Ferro, Karla Priscila Viera, Duarte, Adriana da Silva Santos, Olalla Saad, Sara Teresinha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810108/
https://www.ncbi.nlm.nih.gov/pubmed/29433559
http://dx.doi.org/10.1186/s13287-017-0765-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810108/
https://www.ncbi.nlm.nih.gov/pubmed/29433559
http://dx.doi.org/10.1186/s13287-017-0765-1

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