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miR-21-5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3

Drug resistance and disease recurrence are major obstacles to the effective treatment of cancer, including gastric cancer (GC). However, the mechanisms of drug resistance remain to be fully elucidated. The present study investigated the roles of microRNA (miR)-21-5p in the doxorubicin (DOX) resistan...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Zhou, Chao, Li, Junhe, Xiang, Xiaojun, Zhang, Ling, Deng, Jun, Xiong, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810196/
https://www.ncbi.nlm.nih.gov/pubmed/29393355
http://dx.doi.org/10.3892/ijmm.2018.3405